This timely special issue of the International Review of Environmental History focuses on animals and epidemics in modern East Asia. The global pandemic of Covid-19 has forced us to think more deeply about the interrelations between animals, both human and non-human, and epidemics. Moreover, the intense attention on East Asia in this context demands that we study the region in the thematic matrix of health, environment, animals, sociocultural traditions, and geopolitics. This collection comprises two parts.